"In the long run, we're all dead." -Keynes
It took generations for a second Motor City to emerge outside of Detroit. New York is still the unchallenged capital of the finance and fashion worlds. There's no "Second Hollywood" in the United States. There's a Reno and an Atlantic City, but neither holds a candle to Las Vegas.
What makes you so certain tech will have an exodus from San Francisco between now and the year of your retirement?