We have a huge "social safety net" here in France and yet we are way less entrepreneurial than in the US. I moved to Peru for 4 years to save some money and then came back to start a business, the entrepreneurial spirit was way strong stronger there even though the social safety net is inexistent.
Fact is, having a social safety net makes people comfortable in their poor economic situation and does not require them to take risks. Even in the US, the number of new companies created each year has decreased as the welfare state has grown.