I agree with most of this letter, but with all due respect, I don't think his geopolitical consequences analysis is correct. The war didn't leave Iran as the dominant player, even if the new Iraq is its ally. Iraq is so weak it is more of a burden to its allies than an asset. In fact the war, as intended, bolstered US allies in the region: Israel, a war criminal apartheid country, and Saudi Arabia, one of the most extremist and radical Muslim countries. These two wrecked havoc at their pleasure after the war and the largely unsuccessful "Arab Springs" (some legitimate, some fabricated by the mentioned 2 new dominant players). The current status of the region is absolutely frightening, mainly due to Saudi Arabia's ISIS, which is why removing sanctions on Iran is so crucial to bring some balance again to the region, but probably it is too late.
I can't stop thinking as I read this how the same christian-right conservatives that put bush in power are also blocking stem cell research that could stand a chance of actually helping this poor guy. I believe I remember bush approving the use of funds for stem cell research. I'd look it up but I'm too disgusted right now.