No, of course not. It's great to imagine that all science is accessible to everyone. It's a great democratizing concept. The trouble is that it's departed from reality.
The reason garage labs produce less than real labs, is more likely due to selection effects. The majority of people passionate about biology probably try to become professional biologists. The people doing experiments in their garages are those who didn't make it, or people totally outside the field. And there's also fewer of them.
That's not to say if you took all the actual biologists and make them work in a garage, they wouldn't produce interesting things.