Eh. I'm no particular Airbnb enthusiast--indeed, I've never used it. However, I have stayed at any of a number of non-chain places around the world from the large to the tiny and I've rarely had a terrible experience. (And some of my worst hotel experience were at large chains.)
Especially for business travel, I do like a degree of predictability but that doesn't mean I feel a desire to restrict my travel to where I can stay in business hotels.