The main use I intended for this is to make it ridiculously easy to make useful developer tools - CLIs come really natural to devs, and so I tried to make something a ton of people could build off of to make a ton of cool tools.
An example of a project I want to get to using it is a database CLI app - it can save your credentials, lets you connect to and query the db, give auto-completed suggestions, etc. This is now really easy to do in Javascript, and you just couldn't do that before very easily.
On your question, yeah - there is something Norton Commander-ish - it's a library called blessed, by Christopher Jeffrey, who's pretty boss at CLI apps: