Sounds more like a crappy setup than a problem with uWSGI itself. I know it has a steep learning curve.

I know that it takes time and effort to change out software pieces that have a long history within an organization (I have some experience in that department) even when a clear and technically superior alternative is available.

I have a drawing of my favorite infrastructure that solves a ton of problems before I code one line of anything.

nginx -> uWSGI -> Python(Django) -> Celery(via RabbitMQ) -> Postgres

It's a bit more complicated than this and redis is missing but it's a nice linear representation of how I like to structure things. The only thing there not lightning-fast is Django but it doesn't need to be. I'm spending most of my time in the other pieces of software.