ZeroDB [“end-to-end encrypted database”] is Open Source
github.com
github.com
But when indexing large texts, it becomes a problem. One way to solve it is instead of using generic serializing for data structures, take real structure into account. Many isinstance() calls cause the CPU bottleneck [http://www.upfrontsystems.co.za/Members/roche/where-im-calli...]. Though, it turns out to be not as bad [http://www.upfrontsystems.co.za/Members/roche/where-im-calli...]
So, things people dreamed about inside ZODB, pretty much :-)