The one choice you can't make is iTunes. Being forced to use that dreadful piece of software is why I gave my first iPhone away after little less than one week. It's abysmally incompetent as a music player. You could probably count the number of codecs it supports on one hand - a core feature of a music player is, well, playing your music. Last time I used it, it still didn't have a media library and dumped tens of thousands of songs into a flat list. You have to have that garbage installed on your machine if you own an iPhone. Not interested.