Worse Is Better
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I've heard of the term lisp machine but I must admit I am not much informed on details. I would bet that if those took off as real hardware, lisp as a language would take off together with them.
If computers were Von-Neumann-Machines, this would be true. Modern computers do a lot behind the scenes, that you have to take into account for performance reasoning. E.g. caches. C's concepts also do not play well with concurrency.
C has it's value. It's just not that easy to reason.