I really like the Fido U2F concept, because it ticks all the right boxes; simple to use, reusable for multiple services without being traceable, multiple hardware vendors, open standard, soon implement in Chrome, Firefox, and Edge (although I am not sure about the status in Edge right now), and cheap.
But this solves logging in with a browser. I have been wondering about things like IMAP for e-mail access. To secure my mail a second factor sounds great, but right now all solutions mean I get 2FA when I log in with a browser, but as soon as I use an e-mail client I am back to username and password (application-specific or otherwise).
Ideally, Fido U2F would be an option to use with IMAP and SMTP as well, so that Thunderbird, Outlook, or Apple Mail can prompt me to touch the U2F key when I get my mail. I have not been able to find much information on this approach yet though. Is it possible? Desirable?
Any insights?