I like to go with Larry David's advice with skipping the small talk and going straight to medium or large talk. I like to open with "so how's your marriage?" Just get right into it.
I think most people are going to be much more comfortable talking about art, philosophy or politics than about their personal life, particularly with a stranger.
[1] https://www.youtube.com/watch?v=qOVWS7r9ADY
And to answer your question, yes.