For example, following the little schemer books, they don't print scheme as the actual ascii you need to type, instead they use typography like bold, italic and greek symbols that you have to replace with the uglier reality to distinguish between things like s-expr from lists. It feels like they are embarrassed by the cludgy real syntax, so they hide it and push the difficulty on to the reader.
To give clojure a whirl, I was prepared for lispy paren extravagance but when translating a small program to my best guess at idiomatic clojure (I'm sure I failed) there were so many non-s-expr syntactic special cases for things like list comprehensions and common macros that the result felt like it was jealous of non-s-expr languages and didn't actually want to be a lisp.
In truth, I believe a strong contrast between different syntactic elements helps readability, so I don't think the s-expr regularity I expected is something I actually want.