the assumed context is sending/reading a message via DNA is equivalent to de novo sequencing with 100% accuracy.
error-correcting via 4x overlap:
how many insertions, deletions, substitutions can it correct for? are some combinations harder to fix than others? for example, three insertions much worse than one deletion, or 5 substitutions, etc.
information storage / information blocks:
i'm guessing the 100bp segments have to do with the limits of hardware sequencing, but what limits the overall message size to 739Kb?
thanks very much for your thoughts!