At a certain point, I think its completely reasonable to base that decision on conscience, or on what you can trivially defend to a neutral observer.
Some of Uber's regulatory battles are complex, but many are laughably transparent. France's 15-minute mandatory delay before you can be picked up by hire cars? They didn't even pretend it was about anything other than protecting a monopoly.
If a regulation has a decent purpose that you feel it's not fulfilling (especially safety), you should probably lobby against it. If the regulation's entire purpose is to manipulate a market, it becomes pretty easy to defend ignoring it.