uBlock Origin can handle hosts files, so you can just add it on the bottom of the Third Party Filters tab. It will auto-update it too.
https://raw.githubusercontent.com/jmdugan/blocklists/master/...
https://raw.githubusercontent.com/jmdugan/blocklists/master/...
With uBO, a "facebook.com" entry in a hosts file will also cause all subdomains of "facebook.com" to also be blocked, so there is no need to list all subdomains as is done here if the goal is to block "facebook.com" with uBO.
If one wants to block Facebook via uBO, I personally advise to do it through dynamic filtering[1]. This way one can always point-and-click to create exceptions on a per-site basis.
[1] https://github.com/gorhill/uBlock/wiki/Dynamic-filtering:-to...
Does uBO optimize these cases, though? E.g. if there's "apps.facebook.com", "connect.facebook.net" and plain "facebook.com", does it collapse to just 1 filter (facebook.com)? I see it says "880 used out of 881" which is the number of entries in the file.