The problem with working from home is that it's very easy to procrastinate or just jerk off with the gazillion of things that attract your attention.
Seriously, HN is a gigantic delicious timesink that has probably cost all of us collectively millions.
It's possible, but what you get back from HN is also enormous; from jobs to interactions with very smart people. I mean, Alan Kay was involved in discussions here, just yesterday!
Heck I'm doing it right now with just a web browser sat at my desk...