It's hard to express how sad it makes me that I'll never see photos of the surface of another inhabited world.
It's conceivable that we will be able to send a probe to Europa that can drill through the ice to sample an alien ocean and maybe even find life!
You can talk to people today who remember life before flight was really around, and for whom the universe was mostly just a background to evening activities. Every time we look out with more modern equipment we find the universe is more and more vibrant.
Alien worlds inhabited by other intelligences than ours would be amazing though.