http://www.inc.com/associated-press/top-20-cities-for-tech-s...
That list excludes biotech, and Boston is one of the top biotech hubs, so I suspect that would boost it even higher.
1. Read https://breakoutlist.com/. If that argument matches your motivations, go to San Francisco.
2. Do you have a (relatively) niche interest, like VR/AR, machine learning, or blockchains? Go where those companies are: San Francisco and New York.
3. Do you want to experience a city where everything happens? Go to New York.
Otherwise, pick Austin. Maybe Seattle depending on weather preferences and distance from friends and family.
I would be hard-pressed to come up with names of 3 successful startups from Austin, and I think most people would be too.