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The performance profile matters. 500000 users on an instagram type site create a COMPLETELY different kind of load compared to 500000 on a geo-enabled realtime many-to-many chat program.

Basically, nodejs server just convert http request to MongoDB queries and pass the json results back (especially he turns plan json result off for MongoDB driver).

I cannot even be convinced there is any job nodejs really works on except pass around the requests. Let me put this way, no matter what language or framework he use, spend 90% of his money on MongoDB is the win for this app.

500,000 users doesn't mean anything. what's the requests/second?

Now all we need is an entirely new software stack that passes flatbuffers end to end since they are BETTER than json (rolls eyes)

it can still be up for debate

Maybe a slow language doesn't matter too much when the majority of the work is conveying data back and forth from the database to the users