This is a simple example setup in a 12-drive enclosure. 9 disks, a global hot-spare disk and two cache drives.
Previously, I would have used straight ZFS mirrors for performance and expandability (raidz VDEVs can't be expanded), but at this scale, the 9-disk 3x3 raidz1 setup consistently outperformed a 10-disk RAID mirror setup in random and sequential I/O.