For a field requiring some creativity as well as learned knowledge, enthusiasm and willingness to learn really matters, and the easiest way to induce enthusiasm is actually to go a little off of the mark and present candidates with an opportunity to learn the role based on their existing strengths. That presents some risk, and it's much harder to make it work as you go for "senior" candidates. But case-by-case, there are always ways to offset that risk if you are creative enough - better ways than putting folks who claim to know everything under the microscope in order to fail them as fast as possible, a process which builds a high level of mistrust.