Wouldn't you have to de-dupe prior to encryption? Sorry if I'm being pedantic. I would just not expect anything to deduplicate once it's encrypted.
If you don't CBC, wherever is on the cloud side will have two files with one block off. Let's assume the file is a txt file. For smaller cipher block sizes, it is becoming very easy to guess your encryption key.
Tldr, you want any attacker to lose any diff ability on your encrypted data.
Good practice for file encryption is to pad some random bytes to the start of a file. This makes known cyphertext attacks much harder.
So encrypting identical files should result in different files and also slightly different length files.