Things we usually discuss (and we have at least 1 person who is more knowledgable/an insider so they can teach others and give context) - Tech, Economics, Geopolitics, Culture, Cinema, Photography, BioTech/Energy etc. The goal is _in depth_ discussions, not just water cooler commentary. But since it's friends, it also becomes your usual facebook chat replacement occasionally.
I know it's not the answer you're looking for (since it's actually private/friends and their friends etc for now) but just thought I'd mention this in the context. Trying to create and maintain a community has been an interesting experience so far. :)