Just like excessive consumption of protein (but with a calorie cap) in healthy people shows no harm, or similar studies on healthy, physically active people.
Diet is just a part of a healthy lifestyle and a huge variety of diets can be healthy. This blaming of particular ingredient or macronutrients is unscientific, I as a skeptic dislike it very much.
Fruits are rich in fiber which slows down the absorption of their more "potent" sugars, not to mention that digestion of that fiber is far more taxing than digestion of something else.
Of course, if I were to eat excessive amount of calories it's quite probable I'd get the same symptoms as those people consuming the equivalent in refined sugars.
If one overconsumes and allows for that useless sugar to circulate, or useless cholesterol, or useless anything from overconsumption, a plethora of interesting metabolic things happen in the body and some of them cause disease.
This is a very nice skeptical stance on how to observe food in this age of non-personalized medicine and nutrition:
note I do not eat any sugar or sweeteners and haven't for years, so maybe that's why I am more sensitive to this
This gave me a serious moment of pause about how much sugar is added to manufactured foods.