Tried to use Wire recently. On both the "native" app and the web one, it takes from 2-5 seconds for my message to appear in the window.
I wanted to use it instead of Hangouts, but I can't if it's 3x slower. They need to do something about it, and they need to do it soon. This has happened since they launched the desktop client, but at first I thought I'd just give them sometime to fix the initial bugs. But it's still as slow as ever.
My guess is their HTML5 app code sucks, so if I were them I'd scrap it and start over with a higher-performance alternative.