Never thought about this, good that it's completely provable:

"If we look at the supporting cast, the 14 most prominent characters are all male before we get to the first woman, Mrs. Krabappel, and only 5 of the top 50 supporting cast members are women.

Women account for 25% of the dialogue on The Simpsons, including Marge and Lisa, two of the show’s main characters. If we remove the Simpson nuclear family, things look even more lopsided: women account for less than 10% of the supporting cast’s dialogue.

A look at the show’s list of writers reveals that 9 of the top 10 writers are male."