...have to trust Intel's publicly available documentation. In other words, this has to be taken on pure faith that it does exactly what they say it does in exactly the way they say it does it, and no more.
The problem with ME is that it consists of unauditable code that could be doing literally anything on the computer, completely transparent to the user. Furthermore, even if there is nothing untoward happening when the chip leaves the fab (again, must be taken on faith), a documented threat is having hardware interdicted, modified, and sent on its way.