I don't know enough about Salesforce beyond a few of its products to imagine scenarios where Twitter has comparably low-friction integrations. Unless Disney makes a concerted effort to give Twitter autonomy...can't see how they could leverage it into something that's not just a loss-leader for entertainment. Maybe additional branding opportunities for ESPN and athletes, as well as another way to broadcast events?
edit: Any reason why Amazon isn't in the mix? Other than the obvious reason that they haven't made noise about it? Would an acquisition of Twitter's size be too unwieldy for Amazon?