Really? I tried doing this search and can't find much. I'm pretty up on the state of the scientific literature on kratom, because I'm in the industry, curious, and have been actively working at improving the dreadful wikipedia article.

There's this case, http://www.sciencedirect.com/science/article/pii/S0924933811... , but it's a case of one. There are some cases of simultaneous kratom and alcohol dependence, but that's not the same thing.

Even the peer reviewed evidence for kratom working for opiate withdrawal is quite weak, despite boatloads of anecdotal evidence. There are studies in mice and some observational studies, but nothing that meets the standards of an FDA clinical trial. Kratom has just not really been seriously studied.

If I'm missing some papers or a body of research, please let me know.