My wife studies Alzheimer's and I hope she will respond here, but I'm afraid she gets too angry by sensationalist stories based on editorials rather than mainline research.
Of course there is inflammation involved. From what I understand talking with her, there is not much mechanistic work done with human tissue; most of it is with mouse models that can only get parts of the disease.
Interesting to check out: the inflammasome: https://en.m.wikipedia.org/wiki/Inflammasome.