I've sat in Aerons for a few years across various jobs and they were always just OK - I felt like they could have been great if I could just adjust a few more things to fit my body better.
When it came time to get a "real" office chair for the home office I decided to go with the Steelcase Leap[1] and I have not regretted it. I had no idea a chair could fit me this well. Everything is adjustable and actually labeled - it's like they actually thought about how people use chairs.
The biggest problem with having a chair as good as the Leap to sit in 90% of the time is the other 10% of the time where I'm somewhere with a terrible generic office chair - I can feel it in my back and legs within a few hours.
Everyone is different but I really can't recommend enough at least trying out the leap.