[1] https://www.newscientist.com/article/dn2352-just-2-5-of-dna-...
I mean, 99% is off limits, but what about 98%? 95%? where's the cut off?
I don't think gene commonality is a useful metric for this. Not really sure what would it be though, and I agree that it seems creepy to do experiments on an animal that looks a lot more like you than a worm or a rat.
But I also think it's appalling the way we treat our food sources and would love for this to improve, regardless of whether they look like me or not, and regardless of the amount of genes we have in common. Just out of basic respect for life (I also don't like cutting trees and plants just because).
Unfortunately I still like meat and bacon and other cow products, and while I try to eat less red meat, it's very hard to do.
Cars kill much more animals each day in any case, for no reason and including lots of humans. Maybe people fairly concerned about animal pain could use their skills and time to solve this much more serious problem. Wouldn't be a great goal? You'll save much more lives in an hour than in an entire life of lab rat rescue.