Oh, how I miss having a working USB stack...
https://opensource.apple.com/source/IOUSBFamily/IOUSBFamily-...
They re-wrote IOUSBFamily (or at least they said they did) and it's buggy as all heck whenever you try use a USB 3 hub (since the 10.9 rewrite).
I'd fix it myself, but it's no longer open source. Plus, to really rub salt in the wound, there's no longer a USB debugging kext. Yay, Apple...