When Arch switched from /usr/bin/python being python 2 to being python 3, buckets of python scripts failed. When downloading third-party python programs, the only way I know to know which version of python to use is to try one and when try the other when it complains about syntax errors.
With a perl-style "use" declaration, the runtime can immediately tell you when you're using the wrong version, or even, in principle, switch to the correct runtime if it's installed.
Hashbangs should refer to a version: e.g. "#!/usr/bin/env python2". Github shows approx. 3M results for "/usr/bin/env python", but less than 200k combined for version-specific hashbangs.