Mostly too expensive AFAIK. I'm fuzzy on the details, but it should be possible to create high-resolution (e.g. X-ray) scans of the chips (as is done by chip design pirates) and compare them to known-good implementations, or images generated based off the chip's open-source design.
I'm looking forward to a future where PC auditing shops are a thing. Take in your machine, and let them verify the contents of every chip and storage unit on your device.