If the 8TB drives don't offer the IO we need we'll have to leave part of them empty. I assume that if you fill them with 2TB they should perform equally well. Word on the street is that Google offers Nearline to fill all the capacity they can't use because of latency restrictions for their own applications.
It is an interesting idea to do SSD cache + SSD storage + HDD instead of just SSD cache + HDD. I'm not sure if Ceph allows for this.