That's an assumption on your part.
An alternate explanation is opioids have been overprescribed for decades now, and that people who've gotten hooked and then cut off by their doctors turned to illegal sources, and that as a result opioids are "around" in a way they haven't been since the 1960s and available for the more adventurous people to try.
"Statistically the people who become addicted to morphine are those who have access to it: doctors, nurses, anyone in contact with black market sources. In Persia where opium is sold without control in opium shops, 70 percent of the adult population is addicted. So we should psychoanalyze several million Persians to find out what deep conflicts and anxieties have driven them to the use of opium?"
This is obviously a very supply-side view of drug abuse and very likely an oversimplification. But so is the view that we should tackle underlying causes first ("fix the broken system") when there is an obvious legal pipeline openly pumping opiates into these states. This is particularly off-base as the effects of opioid addiction are now a secondary cause for more opioid addiction (i.e. 'everyone is doing it', 'there are now plenty of dealers', etc.). So much of this is a cycle. I don't disagree about treating the 'broken system' but turning off the pipeline at the corporate level is a huge opportunity to improve things.
By all means, let's work on fixing unemployment and hopelessness in these United States. But let's feel free to shut down a couple brazenly unethical corporate outfits along the way.
The baby boomers also did an excellent job instilling sex, drugs and rock 'n roll as the core set of values in the west. Hedonism is glamorized, reading books not so much.
The infrastructure required to succeed in small towns exists. It's called the Internet and it's a one way ticket to success if you put the effort in to use it and have the strength to go against local culture.