I am in the same situation. People tell me all the time how lucky I am to work remotely, and I was excited when it started. But it definitely has some drawbacks that I didn't expect, especially in the mental health department.
Webex/Hangouts/GTM is fine for 90% of the banal, communication meetings. But it really fails for any design meetings that need a whiteboard. I have tried getting my team to use some alternatives, but there is always some eye rolling, and it never sticks around. It doesn't help that the majority of our team is onsite, so any alternative is 100% for my benefit. Also I haven't found an app that can compete with the tactile feeling of a physical board.
Also I feel like I miss out on the "water cooler" talk. Any sort of communication I have is very formal. My team doesn't like using chat casually, so it really hampers my ability to form relationships with them.
Finally, time management is an issue. When you have an office, its much easier to turn on and off. When I am at home too many mornings start late, and too many evenings run long.