You lose all the good parts of clojure when you go into the js runtime; stm, parallel processing, java interop, hot reloading, and it pulls in some really quite large js dependencies, and it's impossible to debug. Even console logging becomes a case of 'convert to readable object and log' using special helpers.
What's the benefit?
I don't see any meaningful reason to use clojure in this context; what's the draw? Why would you bother over any other compiles-to-js language?
You.. just like the syntax? That's the best answer I've gotten so far.