"Normal people who have happy, functional lives do not meditate or take micro doses of LSD."
Actually, they do. Especially meditation. Sometimes that is why they meditate - is because it keeps them healthy and happier. After all, a sign of a "normal, happy, functional" person is that they handle their stress. Additionally, many more people meditate as a course of religion, though sometimes they use the word prayer instead.
Happy, normal, functional people that are also curious might do micro doses of lsd just to see how it affects their life. Or they might have been doing ti for years to treat their illness so they can be that happy, functional person. Just like folks take anti-depressants daily and you assume they are normal people with happy, functional lives. I don't always react well to meditation, but some folks do. Seriously.
"... with hallucinogenic substances, that usually means the base mood - happy or sad - gets amplified"
Sure, for some folks, this stuff happens. But again, some folks react differently to therapy and "normal" psychiatric drugs, so I'm not sure why folks think the "party drugs" would be different in that respect. And obviously dosage is important: A teaspoon of cough syrup will produce different reactions than drinking the whole bottle. For what it might help, I will notice the normal, everyday "anxiety" coming back while hallucinogens are wearing off, but it really isn't a big deal for me. I wake up the next day feeling like I*ve been able to massage my brain - like it has been all limbered up for use, and the effects last for some time.