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So 5 letter codes are all taken now?

How do you propose to make pairs out of an odd number? Each nucleotide binds to only one other nucleotide.

romesburg made 5 letter pairs, by allowing let's say a third one called "P" for no good reason, to do the following matches:

A:T T:A C:G G:C P:P

Nucleotide that binds only to itself.

Damn!