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We at engageSPARK moved from jQuery mess to Ractive.js, which we're quite happy with. The UI components don't cause us much stress, because they're conceptually simple. What gives us headaches now is the data flow (stores and actions using reflux), so we're now thinking about remodeling this, and while doing so moving to redux. The particular technology is less often the problem, but how it's used, and that's been true for us, too.

This is the sweet spot that my company is going for, been doing React for 2 years now and find it interesting the companies we run into

Angular 1 + CoffeeScript -> React + TypeScript here. Mostly positive experience, though taking sigificantly longer than we planned.