Great product idea. At work we use Skype for business and it's a disaster - especially bad is it seemingly randomly says 'your device is causing poor audio quality' and mutes you. The only way to recover is to dial out and in. Before that it was the AT&T solution - such an ugly application with poor usability. If Amazon really polish this product and provide a great user experience and quality they could pick up a lot of business.

Edit: there's a problem here. Skype for business allows up to 250 participants. The AT&T solution (webex maybe) allows, I think, an unlimited number. Amazon Chime has a limit of 250 people. This wouldn't cut it for presentations in large companies e.g. announcement of annual results or divisional virtual 'town hall'