As far as my own issues go, I think you're speaking from the perspective of someone who has no medical issues and assuming that everyone else is similarly healthy. I have rheumatoid arthritis and hypermobile ehlers-danlos syndrome (amongst other problems). I try to keep fit, have special shoes and joint supports, do everything my physiotherapist tells me to do, and I exercise fairly intensely for at least an hour a day. But ultimately, I have physical limits that despite continual medical intervention, have proven resistant to treatment besides painkillers. In the last month alone, I've been to hospital 6 times. There's a good chance I won't be able to walk more than a few hundred metres by the time I'm 30, and currently if I try to push myself too hard, I typically end up injuring myself and needing to go to hospital.
A computer, for me, and other people like me, can be one of the most transformative purchases of our lives. On a computer, nobody knows you're disabled and you can do almost everything that an able-bodied person can. Arthritis can be a problem, but heated gloves help a lot with that.