I'm sure someone's maxed the strategy, but playing I would always try to figure out when I got to those forced-guess situations which click had the lowest probability of being a mine. I.e., there were squares that you knew were 1/2 or 1/3 chance, you knew how many total unrevealed mines and number of unrevealed squares. So you could calculate the odds on any given square.
One of those problems I always wanted to work on on my own, knowing that someone somewhere probably had a much better solution.