Where are you getting this? Did you account for the fact that the average cortical neuron fires 0.16 times per second? [1] Put in terms of gigaherz, that is -- haha just kidding about gigaherz, that is 0.16 herz per neuron. Times 100 billion neurons. "Combined with the observation that 90% of neurons rarely fire" so you actually might not need to touch all 100 billion of them in a cycle.
100 billion * 0.16 gets you literally 16 gigahertz. This is four cores running at 4 gigaherz. Memory can be heavily compressed if necessary, without slipping out of the realtime budget.
People don't seem to get that these are ANALOG SIGNALS. These neurons aren't etched in silicon. Simulating that is like simulating a mechanical watch or something - with 100 billion pieces. Your guess is ridiculously too-high.
Do you know how long it takes for a signal to cross from one half of the brain to the other? 100 m/s is widely reported progation speed limit, and the average brain length is 167 mm[2] . That means you get 167 mm / 10000 mm = 1.67 milliseconds. That's long enough to cross a server room approximately 25,000 times.
(I divided 20meters by C, getting 66 ns - the time at speed of light to cross a 20 meter room, and this value goes into 1.67 ms 25,032 times.)
All of my numbers here are super-conservative, above-all the fact that I said only 1,000 server rooms were able to do this today. It's considerably higher.
We're ahead of the computational budget required, not behind it. I simply disagree with your calculation.
The rest of this paragraph is sarcastic: When mentioning that there's a non-zero chance that neurons use quantum mechanical effects (the way our etched silicon does, since gates are so small now that this has to be accounted for), you forget to also mention that there's a non-zero chance that souls are connected to brains using an as-yet unidentified organ and therefore nothing in the brain can be simulated given any amount of computational power. I mean, the chances of that aren't zero, right?
[1] "Based on the energy budget of the brain, it appears that the average cortical neuron fires around 0.16 times per second" - http://aiimpacts.org/rate-of-neuron-firing/
[2] https://www.disabled-world.com/artman/publish/brain-facts.sh...