1) Guile has no Global Interpreter Lock.
2) Guile is a scheme, so it is homo-iconic cf. https://en.wikipedia.org/wiki/Homoiconicity
3) Scheme (and lisp in general) are nice to write Domain Specific Languages.
4) Guile doesn't have a particular overhead for calling simple functions which makes it possibly as fast as C.
5) Guile has a very powerful object oriented programming framework beating by far Python and Ruby OO systems.
6) Guile is optimised for immutability which makes it for safer code.
7) Guile has Guix which has 'guix pack' command which is awesome cf. http://git.savannah.gnu.org/cgit/guix.git/tree/doc/guix.texi...
8) Guile has a lot of supporters cf. https://lists.gnu.org/mailman/listinfo/guile-user
9) Guile has awesome maintainers
Also, there is not a lot of packages. But programs written in Guile or using Guile tend to be of higher quality, cf. http://guildhall.hypermove.net/ and http://sph.mn/content/3e73