Ask SpaceX, General Electric, and the thousands of other companies that rely heavily on science.
And before a discovery is made literally nobody knows how it might change the world. I somehow doubt a thousand investors could have better predicted the future value of the transistor any better than the handful of electrical engineers working on that frontier.
But when Einstein was working on Relativity nobody could have foreseen what it would make possible. In that case the discovery was made and then eventually the business sector found a way to sell it, decades afterwards. Today we know what GPS makes possible so we know what it's worth, but in 1905 there was basically no market value for it.