Having been on the ground floor of 3 startups, the biggest issues wasn't salary it was health care, the only people that you can recruit are those young enough not to care, either because they are single or they don't have children. If you want to hire experienced employees the roadblock will be health care. I've lost more people than I can count due to health care issues.
Big businesses actually like to provide health care, they bitch and moan, but if they didn't want to provide it they would drop it. Big business controls the job market by providing health care, it limits employee's freedom to change jobs and start companies. Business provided health care also makes our products and services more expensive decreasing our ability to compete globally.